Wave defense with an RTS command layer. Your drones fight on their own until you take the controls. Mine the wreckage, draft upgrades between waves, and hold the line against an onslaught of asteroids.
Draw trade lanes across a single seamless universe drawn in symbols and lines, and let your ships mine, haul and sell on their own. Chase the materials you lack and the regions you want, push your network outward, and hold the lanes against pirates.